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Director, Division of Systems Toxicology closed

The U.S. Department of Health and Human Services, Food and Drug Administration (FDA), National Center for Toxicological Research (NCTR), Office of Research is seeking to hire a highly qualified scientific leader for the position of Director, Division of Systems Toxicology (DST). The successful candidate will be expected to lead the DST scientists in multi-disciplinary teams of six Centers of Excellence including Centers for Functional Genomics, Proteomics, Metabolomics, Hepatotoxicity, Toxicoinformatics and Chemistry. The successful applicant will be expected to provide research leadership, technical expertise and functional area mentorship for the inclusion of OMICs (genomic, transcriptomic, proteomic, and metabolomic), bio-imaging techniques, nanotechnology and informatic tools to support regulatory decisions including use in studies for the development of safe and effective drugs, veterinary medicines, medical devices and foods associated with the FDA's Critical Path Initiative. The fundamental idea of the Critical Path Initiative is to reduce the uncertainty about product performance throughout the product life cycle through scientific research.

The incumbent will address agency Critical Path scientific issues using a systems approach that links data from "OMICs" technologies with in vivo data to provide a comprehensive mechanistic assessment to predict and evaluate the safety of FDA regulated products.

The NCTR, located approximately 30 miles south of Little Rock, Arkansas, conducts FDA mission-related research that is of critical importance for the Agency to develop a scientifically sound basis for regulatory decisions. Over 110 Ph.D. scientists and 400 support scientists, on-site-contractors and administrative staff make up a dynamic group of professionals in the NCTR organization. Undergraduate and graduate students, post-doctoral fellows and visiting scientists also pursue education and research opportunities in a multi-disciplinary team atmosphere. For more information on NCTR research and training activities, visit http://www.fda.gov/NCTR.

In the Division Director-level position, the incumbent will be expected to be a visionary leader and to establish a nationally recognized research program in systems toxicology to support the Agency's mission. The appointee will represent, manage and provide leadership to DST multi-disciplinary teams of toxicologists, biologists, chemists, molecular biologists and toxicoinformatics scientists.

The Division Director will perform the full range of administrative duties required to manage and supervise a diverse staff of professional research scientists and technical support staff with expertise in areas including, but not limited to, biology, chemistry, molecular biology, toxicoinformatics, and computational chemistry. The incumbent is responsible for recruiting new senior, support, and postdoctoral staff to maintain a state-of the art systems toxicology research program. The Director will participate in the development of intermediate and long-range research plans and goals, evaluates specific research proposals, conducts employee appraisals, and identify budget and facility needs and critiques manuscripts and abstracts. The incumbent will be responsible for furthering the goals of equal employment opportunity by adhering to nondiscriminatory employee practices.

The position requires a Ph.D., M.D. or equivalent with demonstrated success in leading a multi-disciplinary team, a strong publication record in peer reviewed journals, relevant administrative experience, and a strong independent research program. Preference will be given to individuals with a demonstrated record of accomplishments in proteomics, metabolomics, functional genomics, or toxicoinformatics. Evidence of effective planning, organization and decision-making capabilities and excellent interpersonal and communication skills is required.

This is an excepted civil service position under Title 42 USC 209(f) with the salary negotiable and commensurate with experience and qualifications (range of $130,000 - $190,000). The candidate must be a U.S. citizen or permanent resident. Benefits include health and life insurance options, retirement, paid holidays, vacation and sick leave. Relocation expenses may or may not be paid in accordance with FDA policy.
Interested individuals should send a letter of application with a curriculum vitae, statement of proposed and current research plans, copies of up to five peer reviewed publications, and names with complete contact information of three references to the attention of Mary Ann Hutchison, Office of Management Services, NCTR, 3900 NCTR Road, Jefferson, AR 72079.

Applications must be postmarked no later than February 15, 2008. FDA is an Equal Opportunity Employer. FDA/NCTR is a smoke free environment.

posted 2008.01.25