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PhD student researcher on Systems Biology in CALSYS closed

PhD student researcher on Systems Biology
(computer scientists, physicists, mathematicians or engineers)
In the FORSYS Junior Research Group for Cancer and Aging (CALSYS)
Systems Biology and Bioinformatics Group
(University of Rostock)
In CALSYS we investigate the role that the p53-p21-pRB, p16-pRB and other signalling
pathways have in the induction and maintenance of senescence growth arrest and how their
responses are combined to decide whether the cell must undergo cell cycle arrest, senescence or apoptosis in response to (cancer or aging related) DNA damage or stress signals. The aim of the project is to improve our understanding of the relation between cancer and aging using a systems biology approach. The project includes two main scientific parts: i) the investigation of the signalling pathways linking cancer with aging, and ii) the development of methodologies for the qualitative global analysis of cell signalling models based on ordinary diffrential equations.

Job description
We look for a doctoral student with a Master Degree in Computer Sciences, Mathematics,
Physics or Engineering interested on getting experience in Systems Biology of cell signalling
systems. Tasks to be performed include:
  • Mathematical modelling of signalling pathways in cancer and aging.
  • Development of methodologies for global qualitative analysis of ODE models, models in cell signalling. Design of a software tool.
  • Design and administration of a webpage.
Degree in Computer Sciences, Mathematics, Physics or Engineering.
Interest in interdisciplinary research in the life sciences.
Fluent English and/or German.
Matlab programming, Java.
Proficient in Computational Biology.
Previous experience in systems biology and in design and implementation of
numerical algorithms and software will be very positively valued.
Willing to travel across Europe.

Salary: E13, full time job (approx. 2.600 Euro/month gross income).
Project starting date: June-July 2008.
Deadline: 25th april 2008
Project duration: 1 years, a possible extension for three more years.

Submit your application (CV, certificates) to:
Dr. Julio Vera Gonzalez
FORSYS Junior Research Group in Cancer and Aging.
Systems Biology and Bioinformatics Group.
Institute for Informatics, University of Rostock.
D-18051 Rostock Germany.
e-Mail: julio.vera @ uni-rostock.de

posted 2008.04.09