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Postdoctoral Fellowship Position at Metrum Institute open

Metrum Institute is seeking a qualified and motivated candidate for a postdoctoral fellowship position.  The fellow will apply modeling and simulation methodologies to continue the development of a systems biology model relating calcium homeostasis and bone remodeling. The purpose of this multiscale model is to simultaneously describesub-cellular mechanisms, multi-organ interactions, and clinical outcomes.  The goal of this model is to provide a workbench to evaluate the ramifications of system perturbations caused by disease state(s),
genetic abnormalities, and therapeutic intervention(s).  Skills to be applied and developed include physiologic modeling, clinical pharmacology, Bayesian methodologies, and various low- and high-level programming languages.

Founded in 2005, Metrum Institute is a nonprofit organization dedicated to the advancement of quantitative modeling and simulation in biomedical research, with particular emphasis on problems in clinical pharmacology and therapeutics. Our efforts include training courses in modeling & simulation techniques/methods, development of quantitative tools and software,
publications, methods and applied research, symposia, and collaboration with the academic community in research and training of fellows and graduate students.  Metrum Institute is dedicated to the promotion, advancement, and dissemination of knowledge through research,
education, and training in quantitative modeling and simulation applied to biomedical research.

The successful candidate will work alongside and interact with the world-class scientific staff of Metrum Institute. Participation in weekly lab meetings and journal clubs will add to the breadth of experiences during the fellowship.

The fellowship appointment is for one year with the possibility of an additional year with mutual agreement. A doctoral degree (Ph.D., PharmD, or M.D.) is required in pharmacokinetics, pharmaceutical sciences, biostatistics, bioengineering or related discipline at the time of appointment. Prior experience with Bayesian and other modeling and simulation tools, programming and statistical training, and an understanding of biological processes is desirable. Applicants must be eligible to work in the United States. Metrum Institute is an equal opportunity employer.

For further information, or to apply (CV / cover letter), please contact:

William R. Gillespie, Ph.D.
Research and Development Director
Metrum Institute
2 Tunxis Road,  Suite 112
Tariffville, CT 06081 USA
billg [at] metruminstitute.org

posted 2010.01.20