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Post-Doctoral Position in Systems Biology: Analysis of the Host Cell Signaling Network Controlling Pathogen Entry into Human Cells closed

A Post-doctoral position is available in the research group of Prof. Christoph Dehio at the Biozentrum of the University of Basel (http://www.biozentrum.unibas.ch/dehio/index.html). This position is part of "InfectX" (http://www.systemsx.ch/projects/systemsxch-projects/research-technology-and-development-projects-rtd/infectx/), a collaborative project funded by SystemsX.ch - the Swiss Initiative in Systems Biology (http://www.systemsx.ch).

The aim of the InfectX project is to use a systems biology approach to decipher the host cell signaling network controlling entry of a diverse set of bacterial and viral pathogens in order to define novel drug targets for anti-infectives. In this context our laboratory will study the host cell signaling pathways controlling entry and intracellular replication of the related bacterial pathogens Bartonella and Brucella. Key technologies and methods applied by the successful candidates are genome-wide RNA interference (RNAi) screens, multi-dimensional fluorescence microscopy, surface- and phospho-proteomics, as well as conventional biochemical and cell biological methods, which in collaboration with computational modelers will facilitate signal transduction pathway reconstruction.

We are looking for highly motivated individuals with a degree in biology or biochemistry and solid knowledge and working experience in cell biology. Experiences in studying eukaryotic signal transduction and/or intracellular trafficking processes are an asset. The positions are funded for a maximum of 3 years. For questions please contact Prof. Christoph Dehio (christoph.dehio @ unibas.ch). Applications should include a letter of motivation, a full c.v., and the names of 2-3 references and be sent electronically to rachel.benzies @ unibas.ch.

Additional Information:
The Biozentrum is an internationally renowned institute for basic life science research. With over 400 employees from 30 countries, it is the largest natural science department of the University of Basel. About 30 research groups engage in interdisciplinary research, and are in close contact with local life sciences industry. The working language at the institution is English. SystemsX.ch is a Swiss research consortium with eight universities and three research institutions. More than 100 research groups devoted to Systems Biology collaborate in 14 Research-, Technology- and Development programs.

posted 2010.12.03